Columbia University Press's multivolume _Prison Notebooks_ is the only complete critical edition of Antonio Gramsci's seminal writings in English. Based on the authoritative Italian edition of Gramsci's work, _Quaderni del Carcere_, this comprehensive translation presents the intellectual as he ought to be read and understood, with critical notes that clarify Gramsci's history, culture, and sources; an index of names; and a contextualization of the thinker's ideas against his earlier writings and letters. This set includes notebooks 1 through 8 with (...) all attendant notes and materials and is an indispensible resource for scholars in the humanities and social sciences. (shrink)

We propose the “microbiota‐inflammasome” hypothesis of major depressive disorder (MDD, a mental illness affecting the way a person feels and thinks, characterized by long‐lasting feelings of sadness). We hypothesize that pathological shifts in gut microbiota composition (dysbiosis) caused by stress and gut conditions result in the upregulation of pro‐inflammatory pathways mediated by the Nod‐like receptors family pyrin domain containing 3 (NLRP3) inflammasome (an intracellular platform involved in the activation of inflammatory processes). This upregulation exacerbates depressive symptomatology and further compounds gut (...) dysbiosis. In this review we describe MDD/chronic stress‐induced changes in: 1) NLRP3 inflammasome; 2) gut microbiota; and 3) metabolic pathways; and how inflammasome signaling may affect depressive‐like behavior and gut microbiota composition. The implication is that novel therapeutic strategies could emerge for MDD and co‐morbid conditions. A number of testable predictions surface from this microbiota‐gut‐inflammasome‐brain hypothesis of MDD, using approaches that modulate gut microbiota composition via inflammasome modulation, fecal microbiota transplantation, psychobiotics supplementation, or dietary change. (shrink)

A mística é um fenômeno presente em quase todas as grandes religiõesdo mundo. No cristianismo, esta manifestação pode ser notada já nos textosSagrados do Novo Testamento: desde os relatos que envolveram os eventos da vidade Jesus às visões escatológicas de João no livro do Apocalipse. Posteriormente,podemos en contrar registros de misticidade no grande movimento dos Pais da Igrejaconhecido como Patrística, se estendendo por toda Idade Média, até alcançar osdias de hoje. Todavia, alguns pesquisadores da antiguidade tardia, procuraramenquadrar o grande nome (...) da Patrística, Santo Agostinho, como o pai da místicacatólica. Outrossim, Agostinho é sumamente conhecido como um grande teólogo,filósofo ou mesmo como um gênio intelectual platônico cristão investigador daVerdade; sendo, porém, bastante diminuto, o número de pesquisadores que sepropõe a verificar se, de fato, há ou não razões, para que ele seja contado entre osgrandes místicos da Igreja. O presente ensaio traz à tona esta polêmica discussão,com o intuito de elucidar o problema que ora se levanta: podemo s considerar SantoAgostinho um místico ou apenas um grande nome da filosofia/teologia cristã? Istoposto, para responder a referida questão problema, nos propomos investigar osprincipais acontecimentos da vida de Agostinho, bem como, os principais textos desua obra, a fim de comprovar algum resquício de misticidade, seja em sua vida oumesmo em suas investigações acerca da Verdade. (shrink)

The study of Buddhist texts can inform us of the way scriptures were composed, as well as illuminate the reasons behind their production. This study examines the phenomenon of borrowing and reusing portions of texts without attributing them to their ‘legitimate authors’ within the Buddhist world of contemporary Tibet. It shows that not only is such a practice not at all infrequent and is often socially accepted, but that it is used in this case as a platform to advance specific (...) claims and promote an explicit agenda. Therefore, rather than considering these as instances of plagiarism, this essay looks at the practice of copying and borrowing as an exercise in intertextuality, intended as the faithful retransmission of ancient truths, and as an indication of the public domain of texts in Tibet. (shrink)

Heidegger has often been considered as the proponent of the end of metaphysics in the post-Hegelian philosophy, due to his persistent attempts to overcome the onto-theological framework of traditional metaphysics. Yet, this dismissal of metaphysical, theological, and religious motives is deeply ambiguous since new forms of metaphysical and religious experience re-emerge in his philosophical works. Heidegger shares this ambiguous relation to the notions of faith and religion with authors such as Nietzsche and Wittgenstein whose works are also marked by a (...) critique of metaphysics and by a characteristic rethinking of the role of faith and religion. In fact, all three still remain, among other things, reference points for contemporary philosophical debates relating to the phenomenon of religion and faith. Rethinking Faith explores how the phenomena of religion and faith are present in the works of Heidegger, Nietzsche, and Wittgenstein, and how these phenomena are brought into play in their discussion of the classical metaphysical motives they criticize. (shrink)

The article pretends to situate basic patterns in order to think the nature of “the epistemological revolution”, having in mind criteria that allow to distinguish and meaning fully take into consideration the place from where one stares and speaks. This supposes to think “the epistemological revolut..

O presente ensaio apresenta, inicialmente, uma sondagem acerca da compreensão do Brasil contemporâneo pelo pensamento de seus intérpretes mais expressivos. Em seguida, analisa o último balanço da cultura brasileira operado pela Tropicália, um movimento que revolveu os traumas residuais da cultura brasileira ao inventar um padrão de compreensão sob novas chaves estéticas e políticas — em particular, a produção musical do movimento. Por fim, o ensaio analisa o disco Tropicália lixo lógico de Tom Zé, lançado em 2012, perseguindo a linha (...) de discos experimentais e de tese do músico. Nele, o artista retoma criticamente aspectos da cultura brasileira atual, conjugados com os temas culturais dissecados pela Tropicália desde 1967. Como a maioria dos ensaios, este se move por indícios e análises tópicas do disco em questão, a contextualizar e a problematizar a construção da identidade nacional. (shrink)

This article shows the close relationship that exists between two fundamental concepts in the theological doctrine of Origen of Alexandria: “fullness” and“participation”. These two concepts have been the subject of many earlier studies. However, they treated the topic in a more restricted sense, exploring very specific aspects of Origenian theology. The originality of this study lies in demonstrating how both concepts recur frequently in his theological thinking, give it a framework and hold his thought together. They consequently systematize and make (...) possible a perfect synthesis of all his thinking. (shrink)

El presente artículo estudia la visión zubiriana de la voluntad en el pensamiento publicado póstumamente de Zubiri, donde aparece un concepto original de libertad como capacidad de autodeterminación de la voluntad.

El presente artículo plantea algunas consideraciones antropológicas sobre la biotecnología y su caracterización en esta era de incertidumbres. Se introduce el concepto de “ética de la emergencia” de Arturo Roig en un esfuerzo por avanzar en el análisis de la tecnobiología.

En este artículo se pretende plantear la posibilidad de una filosofía que useel género teatral como forma consciente de expresión, no solo para ilustraro hacer atractiva las ideas, sino para hacer propiamente filosofía. El diálogopermite establecer el desarrollo de ideas en forma de conflicto o de entrelazamientode acciones como una filosofía teatral. El debate filosófico quemuestra las circunstancias del encuentro de los personajes y cómo estas sedesarrollan, aunque solo sea implícitamente, construyen una filosofía dondelos hechos particulares se integran y, de (...) ese modo, hacen posible un modoparticular de hacer filosofía. (shrink)